Using ADCT in clinical studies
Atopic Dermatitis Control Tool (ADCT) has been scientifically validated to assess atopic dermatitis control status in adult and adolescent patients (12 years and older).1,2 ADCT can indicate changes in control status within a patient over a time period of several months.2
A modified version of the ADCT for children with AD aged 8-11 years and another for caregivers of children with AD aged 6 months to 11 years have also been developed,3 and are currently pending threshold validation.3
Why assess long-term control of AD in clinical studies?
The Harmonising Outcome Measures for Eczema (HOME) initiative identified long-term control as one of the four core outcome domains that should be measured and reported in all atopic dermatitis trials:
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HOME has recommended ADCT as a core outcome instrument for measuring long-term control of atopic dermatitis in clinical trials4
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HOME encourages the use of standardized measures of core outcome domains to enable trials to be compared and combined in meta-analyses, thus enabling evidence-based analysis of clinical data4
Is ADCT free of charge?
Yes, ADCT is made available on an Open Access scheme. If you are planning to use ADCT in a clinical study, please use the following link to request the correct version of ADCT and the copyright from MAPI Research Trust:
https://eprovide.mapi-trust.org/instruments/atopic-dermatitis-control-toolYou will be asked to complete a request form describing the intended use of the tool. The information provided with this form helps to ensure that ADCT is used in the context and with the standards it has been designed and validated for.
Footnotes
- Pariser DM, et al. Curr Med Res Opin. 2020;36(3):367-376.
- Simpson E, et al. BMC Dermatol. 2019;19(1):15.
- Chuang CC, et al. Dermatol Ther (Heidelb). 2024;14(12):3261-3271.
- Leshem YA, et al. JAMA Dermatol. 2022;158(12):1429-1435.